Invention Grant
US07135612B2 Identification of the gene causing the mouse scurfy phenotype and its human ortholog
失效
鉴定引起小鼠scurfy表型的基因及其人类直向同源物
- Patent Title: Identification of the gene causing the mouse scurfy phenotype and its human ortholog
- Patent Title (中): 鉴定引起小鼠scurfy表型的基因及其人类直向同源物
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Application No.: US10934250Application Date: 2004-09-03
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Publication No.: US07135612B2Publication Date: 2006-11-14
- Inventor: Mary E Brunkow , Eric W Jeffery , Kathryn A Hjerrild , Fred Ramsdell
- Applicant: Mary E Brunkow , Eric W Jeffery , Kathryn A Hjerrild , Fred Ramsdell
- Applicant Address: GB Slough
- Assignee: UCB SA
- Current Assignee: UCB SA
- Current Assignee Address: GB Slough
- Agency: Davis Wright Tremaine LLP
- Agent Jane E. R. Potter; Kerry Fluhr
- Main IPC: A01K67/027
- IPC: A01K67/027 ; A01K67/00 ; C12N15/00 ; C12N5/00 ; C12N15/63 ; C12P21/06
Abstract:
Isolated nucleic acid molecules are provided which encode Fkhsf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Utilizing assays based upon the nucleic acid sequences disclosed herein (as well as mutant forms thereof), numerous molecules may be identified which modulate the immune system.
Public/Granted literature
- US20050106601A1 Identification of the gene causing the mouse scurfy phenotype and its human ortholog Public/Granted day:2005-05-19
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