发明授权
- 专利标题： Sulfonamide lactam inhibitors of FXa and method
- 专利标题（中）： FXa的磺酰胺内酰胺抑制剂及方法
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申请号： US10374299申请日： 2003-02-26
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公开(公告)号： US07166586B2公开(公告)日： 2007-01-23
- 发明人: Stephen P. O'Connor , Michael Lawrence , Yan Shi , Philip D. Stein
- 申请人： Stephen P. O'Connor , Michael Lawrence , Yan Shi , Philip D. Stein
- 申请人地址： US NJ Princeton
- 专利权人： Bristol Myers Squibb Co.
- 当前专利权人： Bristol Myers Squibb Co.
- 当前专利权人地址： US NJ Princeton
- 代理商 Ronald S. Hermenau; Stephen B. Davis; Jing G. Sun
- 主分类号： C07D41/02
- IPC分类号： C07D41/02 ; A61K31/454 ; A61K31/445
摘要：
Sulfonamide lactams of the following formula wherein X, R1, R2, R3, R4, R4a, R5, R5a, R6, R6a, R7 and R8 are as described herein, are provided which inhibitors of Factor Xa and are useful as anticoagulants in the treatment of cardiovascular diseases associated with thromboses.
公开/授权文献
- US20040186134A1 Sulfonamide lactam inhibitors of FXa and method 公开/授权日：2004-09-23