- 专利标题： Inhibitors of cathepsin S
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申请号： US10868459申请日： 2004-06-10
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公开(公告)号： US07173051B2公开(公告)日： 2007-02-06
- 发明人: Hong Liu , David Tully , Phillip Alper , Robert Epple , Arnab Chatterjee , Michael Roberts
- 申请人： Hong Liu , David Tully , Phillip Alper , Robert Epple , Arnab Chatterjee , Michael Roberts
- 申请人地址： BM Hamilton HM LX
- 专利权人： IRM, LLC
- 当前专利权人： IRM, LLC
- 当前专利权人地址： BM Hamilton HM LX
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： A61K31/423
- IPC分类号： A61K31/423 ; A61K31/403 ; A61K31/428 ; C07D263/58 ; C07D227/04 ; C07D417/02 ; C07D498/02
摘要：
The present invention provides compounds, compositions and methods for the selective inhibition of cathepsin S. In a preferred aspect, cathepsin S is selectively inhibited in the presence of at least one other cathepsin isozyme. The present invention also provides methods for treating a disease state in a subject by selectively inhibiting cathepsin S.
公开/授权文献
- US20050049244A1 Inhibitors of cathepsin S 公开/授权日：2005-03-03
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