发明授权
- 专利标题： Process for the synthesis of oligomeric compounds
- 专利标题（中）： 低聚化合物的合成方法
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申请号： US11025791申请日： 2004-12-28
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公开(公告)号： US07186822B2公开(公告)日： 2007-03-06
- 发明人: Vasulinga Ravikumar , Muthiah Manoharan , Daniel C. Capaldi , Achim Krotz , Douglas L. Cole , Andrei P. Guzaev
- 申请人： Vasulinga Ravikumar , Muthiah Manoharan , Daniel C. Capaldi , Achim Krotz , Douglas L. Cole , Andrei P. Guzaev
- 申请人地址： US CA Carlsbad
- 专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人： Isis Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Carlsbad
- 代理机构： Woodcock Washburn LLP
- 主分类号： C07H21/00
- IPC分类号： C07H21/00
摘要：
Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related contaminants.
公开/授权文献
- US20050182251A1 Process for the synthesis of oligomeric compounds 公开/授权日：2005-08-18
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