发明授权
US07202342B1 Compositions and methods for the therapy and diagnosis of prostate cancer
失效
用于治疗和诊断前列腺癌的组合物和方法
- 专利标题： Compositions and methods for the therapy and diagnosis of prostate cancer
- 专利标题（中）： 用于治疗和诊断前列腺癌的组合物和方法
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申请号： US09570737申请日： 2000-05-12
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公开(公告)号： US07202342B1公开(公告)日： 2007-04-10
- 发明人: Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler
- 申请人： Jiangchun Xu , Davin C. Dillon , Jennifer L. Mitcham , Susan L. Harlocker , Yuqiu Jiang , Michael D. Kalos , Gary R. Fanger , Marc W. Retter , John A. Stolk , Craig H. Day , Thomas S. Vedvick , Darrick Carter , Samuel X. Li , Aijun Wang , Yasir A. W. Skeiky , William T. Hepler
- 申请人地址： US MT Hamilton
- 专利权人： Corixa Corporation
- 当前专利权人： Corixa Corporation
- 当前专利权人地址： US MT Hamilton
- 代理机构： Seed IP Law Group PLLC
- 主分类号： C07K16/00
- IPC分类号： C07K16/00 ; A61K39/395
摘要：
Compositions and methods for the therapy and diagnosis of cancer, such as prostate cancer, are disclosed. Compositions may comprise one or more prostate-specific proteins, immunogenic portions thereof, or polynucleotides that encode such portions. Alternatively, a therapeutic composition may comprise an antigen presenting cell that expresses a prostate-specific protein, or a T cell that is specific for cells expressing such a protein. Such compositions may be used, for example, for the prevention and treatment of diseases such as prostate cancer. Diagnostic methods based on detecting a prostate-specific protein, or mRNA encoding such a protein, in a sample are also provided.
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