发明授权
- 专利标题： Four-helical bundle protein zsig81
- 专利标题（中）： 四螺旋束蛋白zsig81
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申请号： US10315379申请日： 2002-12-09
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公开(公告)号： US07223564B2公开(公告)日： 2007-05-29
- 发明人: Christopher S. Piddington , James W. West , Richard D. Holly , Steven K. Burkhead
- 申请人： Christopher S. Piddington , James W. West , Richard D. Holly , Steven K. Burkhead
- 申请人地址： US WA Seattle
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： US WA Seattle
- 代理商 Deborah A. Sawislak
- 主分类号： C12N15/16
- IPC分类号： C12N15/16 ; C12N15/63 ; C12N5/00 ; C07K14/475 ; C07K4/12
摘要：
This present invention is directed to polypeptide and polynucleotide molecules that encode a four-helical bundle cytokine. The cytokine has been designated zsig81, and has restricted expression in primarily heart, lung and liver. zsig81 has been shown to stimulate proliferation of hematopoietic cells and will be useful expansion of these cells, as well as conditions associated with hematopoietic cells. The invention is directed to antibodies and methods of making zsig81 polypeptides, as well.
公开/授权文献
- US20040059095A1 Four-helical bundle protein zsig81 公开/授权日：2004-03-25