Invention Grant
- Patent Title: EG-VEGF nucleic acids and polypeptides and method of use
- Patent Title (中): EG-VEGF核酸和多肽及其使用方法
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Application No.: US10027603Application Date: 2001-12-19
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Publication No.: US07264801B2Publication Date: 2007-09-04
- Inventor: Napoleone Ferrara , Colin Watanabe , William I. Wood , Theresa Shek
- Applicant: Napoleone Ferrara , Colin Watanabe , William I. Wood , Theresa Shek
- Applicant Address: US CA South San Francisco
- Assignee: Genentech, Inc.
- Current Assignee: Genentech, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Merchant & Gould P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/00 ; C07K16/22 ; G01N33/53
Abstract:
The present invention is directed to novel polypeptides designated herein as EG-VEGF and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided herein are methods of screening for modulators of EG-VEGF. Furthermore, methods and related methods of treatment are described herein which pertain to regulating cellular proliferation and chemotaxis.
Public/Granted literature
- US20020192634A1 EG-VEGF nucleic acids and polypeptides and methods of use Public/Granted day:2002-12-19
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