Invention Grant
- Patent Title: Germinal center kinase proteins, compositions, and methods of use
- Patent Title (中): 生发中心激酶蛋白，组合物和使用方法
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Application No.: US10493164Application Date: 2002-10-21
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Publication No.: US07300780B2Publication Date: 2007-11-27
- Inventor: Cindy Leo , Ying Luo , Xiang Xu , Simon Yu
- Applicant: Cindy Leo , Ying Luo , Xiang Xu , Simon Yu
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Townsend and Townsend and Crew, LLP
- International Application: PCT/US02/33845 WO 20021021
- International Announcement: WO03/040409 WO 20030515
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C07K1/00
Abstract:
The present invention provides compositions and methods for modulating cell proliferation, survival, morphology, and migration. Nucleic adds encoding proteins and proteins so encoded which are capable of modulating proliferation, survival, morphology and migration in mammalian cells are provided. Compositions and methods for the treatment of disorders related to cell proliferation, survival, morphology and migration are also provided. Prophylactics and methods for the prevention of such disorders are also provided. Also provided are compositions and methods for diagnostic and prognostic determination of such disorders. Further provided are assays for the identification of bioactive agents capable of modulating proliferation, survival, morphology and migration in mammalian cells.
Public/Granted literature
- US20050019771A1 Novel germinal center kinase proteins, compositions, and methods of use Public/Granted day:2005-01-27
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