Invention Grant
- Patent Title: Diamino-pyrimidines and their use as angiogenesis inhibitors
- Patent Title (中): 二氨基嘧啶及其作为血管生成抑制剂的用途
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Application No.: US10506447Application Date: 2003-02-28
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Publication No.: US07338959B2Publication Date: 2008-03-04
- Inventor: Stanley Dawes Chamberlain , Mui Cheung , Holly Kathleen Emerson , Neil W. Johnson , Kristen Elizabeth Nailor , Douglas McCord Sammond , Marcus Semones
- Applicant: Stanley Dawes Chamberlain , Mui Cheung , Holly Kathleen Emerson , Neil W. Johnson , Kristen Elizabeth Nailor , Douglas McCord Sammond , Marcus Semones
- Applicant Address: US PA Philadelphia
- Assignee: SmithKline Beecham Corporation
- Current Assignee: SmithKline Beecham Corporation
- Current Assignee Address: US PA Philadelphia
- Agent John L. Lemanowicz; Jennifer L. Fox
- International Application: PCT/US03/06022 WO 20030228
- International Announcement: WO03/074515 WO 20030912
- Main IPC: C07D239/48
- IPC: C07D239/48 ; C07D403/12 ; C07D403/14 ; A61K31/506 ; A61K31/4184 ; A61P35/00
Abstract:
Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR-2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.
Public/Granted literature
- US20050234083A1 Diamino-pyrimidines and their use as angiogenesis inhibitors Public/Granted day:2005-10-20
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