发明授权
- 专利标题: Labelled nucleotides
- 专利标题(中): 标记核苷酸
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申请号: US10525399申请日: 2003-08-22
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公开(公告)号: US07414116B2公开(公告)日: 2008-08-19
- 发明人: John Milton , Silke Ruediger , Xiaohai Liu
- 申请人: John Milton , Silke Ruediger , Xiaohai Liu
- 申请人地址: GB Nr. Saffron Walden, Essex
- 专利权人: Illumina Cambridge Limited
- 当前专利权人: Illumina Cambridge Limited
- 当前专利权人地址: GB Nr. Saffron Walden, Essex
- 代理机构: Klauber & Jackson LLC
- 国际申请: PCT/GB03/03690 WO 20030822
- 国际公布: WO2004/018493 WO 20040304
- 主分类号: C07H21/00
- IPC分类号: C07H21/00 ; C07H21/02 ; C12Q1/68 ; C12P19/34 ; C07H19/04
摘要:
The invention provides a nucleotide or nucleoside having a base attached to a detectable label via a cleavable linker, characterised in that the cleavable linker contains a moiety selected from the group comprising: Formula (I) wherein X is selected from the group comprising O, S, NH and NQ wherein Q is a C1-10 substituted or unsubstituted alkyl group, Y is selected from the group comprising O, S, NH and N(allyl), T is hydrogen or a C1-10 substituted or unsubstituted alkyl group and * indicates where the moiety is connected to the remainder of the nucleotide or nucleoside).
公开/授权文献
- US20060160081A1 Labelled nucleotides 公开/授权日:2006-07-20
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