发明授权
- 专利标题： Factor IXa for the treatment of bleeding disorders
- 专利标题（中）： 因子IXa用于治疗出血性疾病
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申请号： US11068596申请日： 2005-02-28
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公开(公告)号： US07425539B2公开(公告)日： 2008-09-16
- 发明人: Shane Donovan , Donald A. Baker
- 申请人： Shane Donovan , Donald A. Baker
- 申请人地址： US IL Deerfield CH Wallisellen, Zurich
- 专利权人： Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人： Baxter International Inc.,Baxter Healthcare S.A.
- 当前专利权人地址： US IL Deerfield CH Wallisellen, Zurich
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： A61K38/00
- IPC分类号： A61K38/00
摘要：
The invention provides a method of treating bleeding disorders in a subject by administration of a preparation enriched for Factor IXa. The Factor IXa can be produced by proteolytically activating recombinantly-produced Factor IX. The invention also provides an improved method for producing Factor IXa from a plasma fraction, which method results in a Factor IXa product containing little or no prekallikrein activity, thus reducing the incidence of undesired side effects in a subject.
公开/授权文献
- US20050209149A1 Factor IXa for the treatment of bleeding disorders 公开/授权日：2005-09-22
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