发明授权
- 专利标题: P-cadherin antibodies
- 专利标题(中): P-钙粘蛋白抗体
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申请号: US11410610申请日: 2006-04-25
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公开(公告)号: US07452537B2公开(公告)日: 2008-11-18
- 发明人: Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
- 申请人: Christopher Todd Bauer , Maureen Jeri Bourner , Melanie Boyle , Gerald Fries Casperson , David William Griggs , Richard David Head , William Dean Joy , Richard Allen Mazzarella , Ralph Raymond Minter , Mark Allen Moffat , Barrett Richard Thiele , Todd Lee Vanarsdale
- 申请人地址: US CA San Diego
- 专利权人: Agouron Pharmaceuticals, Inc.
- 当前专利权人: Agouron Pharmaceuticals, Inc.
- 当前专利权人地址: US CA San Diego
- 代理商 Bryan C. Zielinski; Matthew J. Pugmire; Galina M. Yakovleva
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K16/00
摘要:
The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that bind to P-cadherin, and that function to inhibit P-cadherin. The invention also relates to heavy and light chain immunoglobulins derived from human P-cadherin antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human P-cadherin antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
公开/授权文献
- US20060240001A1 P-cadherin antibodies 公开/授权日:2006-10-26