发明授权
- 专利标题: Nucleic acid delivery
- 专利标题(中): 核酸递送
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申请号: US11442653申请日: 2006-05-25
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公开(公告)号: US07462351B2公开(公告)日: 2008-12-09
- 发明人: Susan E. Conroy , Heidrun Engler , Daniel C. Maneval
- 申请人: Susan E. Conroy , Heidrun Engler , Daniel C. Maneval
- 申请人地址: US CA Palo Alto GB Ruddington
- 专利权人: Canji, Inc.,Innovata Limited
- 当前专利权人: Canji, Inc.,Innovata Limited
- 当前专利权人地址: US CA Palo Alto GB Ruddington
- 代理机构: Townsend and Townsend and Crew LLP
- 主分类号: A61K48/00
- IPC分类号: A61K48/00 ; C12N15/861
摘要:
The present invention provides formulations and methods to enhance the delivery of nucleic acids to cells. Formulations comprising dextrin polymers in combination with sugars provide enhanced delivery of nucleic acids, particularly eucaryotic expression vectors, demonstrate enhanced delivery of nucleic acids to cells in vivo. The present invention also provides methods of treatment in combination with such formulations.
公开/授权文献
- US20070009485A1 Nucleic acid delivery 公开/授权日:2007-01-11
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