发明授权
- 专利标题: Adipose-derived stem cells and lattices
- 专利标题(中): 脂肪来源的干细胞和晶格
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申请号: US10740315申请日: 2003-12-17
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公开(公告)号: US07470537B2公开(公告)日: 2008-12-30
- 发明人: Marc H. Hedrick , Adam J. Katz , Ramón Llull , J. William Futrell , Prosper Benhaim , Hermann Peter Lorenz , Min Zhu
- 申请人: Marc H. Hedrick , Adam J. Katz , Ramón Llull , J. William Futrell , Prosper Benhaim , Hermann Peter Lorenz , Min Zhu
- 代理机构: Mandel & Adriano
- 主分类号: C12N5/00
- IPC分类号: C12N5/00
摘要:
The present invention provides adipose-derived stem cells (ADSCs), adipose-derived stem cell-enriched fractions (ADSC-EF) and adipose-derived lattices, alone and combined with the ADSCs of the invention. In one aspect, the present invention provides an ADSC substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The ADSCs can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the ADSCs can be expanded and cultured to produce molecules such as hormones, and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides an adipose-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.
公开/授权文献
- US20050153441A1 Adipose-derived stem cells and lattices 公开/授权日:2005-07-14