发明授权
- 专利标题： Membrane arrays and methods of manufacture
- 专利标题（中）： 膜阵列和制造方法
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申请号： US11026371申请日： 2004-12-30
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公开(公告)号： US07473533B2公开(公告)日： 2009-01-06
- 发明人: Alain R. E. Carre , Alexander M. Efremov , Ye Fang , Yulong Hong , Valerie Lacarriere , Joydeep Lahiri , Fang Lai , John C. Mauro , Srikanth Raghavan , Brian L. Webb
- 申请人： Alain R. E. Carre , Alexander M. Efremov , Ye Fang , Yulong Hong , Valerie Lacarriere , Joydeep Lahiri , Fang Lai , John C. Mauro , Srikanth Raghavan , Brian L. Webb
- 申请人地址： US NY Corning
- 专利权人： Corning Incorporated
- 当前专利权人： Corning Incorporated
- 当前专利权人地址： US NY Corning
- 代理商 Thomas R. Beall; John L. Haack
- 主分类号： G01N17/04
- IPC分类号： G01N17/04 ; G01N33/566 ; C12Q1/00 ; C07K14/705
摘要：
The invention relates to G protein-coupled receptor (GPCR) microarrays on porous substrates for structural or functional analyses of GPCRs, and methods of preparing porous substrate surfaces for receiving membranes that comprise GPCRs. In one embodiment, a GPCR microarray of the invention comprises a membrane adhered to an upper surface of a porous substrate, the membrane spanning across a plurality of pores on the porous substrate to form a plurality of cavities having sufficient geometry to permit entry of assay reagents into each cavity, thereby allowing access of assay reagents to both sides of GPCR in the membrane.
公开/授权文献
- US20060147993A1 Membrane arrays and methods of manufacture 公开/授权日：2006-07-06
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