发明授权
US07501117B2 Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
有权
表现出von Willebrand因子（vWF）蛋白酶活性的组合物，其包含具有氨基酸序列AAGGILHLELLV的多肽链
- 专利标题： Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
- 专利标题（中）： 表现出von Willebrand因子（vWF）蛋白酶活性的组合物，其包含具有氨基酸序列AAGGILHLELLV的多肽链
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申请号： US11166288申请日： 2005-06-23
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公开(公告)号： US07501117B2公开(公告)日： 2009-03-10
- 发明人: Bernhard Laemmle , Helena Elisabeth Schaller-Gerritsen , Miha Furlan , Peter Turecek , Hans-Peter Schwarz , Friedrich Scheiflinger , Gerhard Antoine , Randolf Kerschbaumer , Luigina Tagliavacca , Klaus Zimmermann
- 申请人： Bernhard Laemmle , Helena Elisabeth Schaller-Gerritsen , Miha Furlan , Peter Turecek , Hans-Peter Schwarz , Friedrich Scheiflinger , Gerhard Antoine , Randolf Kerschbaumer , Luigina Tagliavacca , Klaus Zimmermann
- 申请人地址： AT Vienna
- 专利权人： Baxter Innovations GmbH
- 当前专利权人： Baxter Innovations GmbH
- 当前专利权人地址： AT Vienna
- 代理机构： Townsend and Townsend and Crew LLP
- 主分类号： A61K35/14
- IPC分类号： A61K35/14 ; A61K38/46 ; C12N9/64 ; C07H21/04
摘要：
The invention relates to vWF cleaving entities having a molecular weight of 180 kD, 170 kD, 160 kD, 120 kD or 110 kD and an N-terminal amino acid sequence of AAGGILHLELLV, vWF cleaving complexes and methods for their production.