Invention Grant
US07501117B2 Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
有权
表现出von Willebrand因子（vWF）蛋白酶活性的组合物，其包含具有氨基酸序列AAGGILHLELLV的多肽链
- Patent Title: Composition exhibiting a von Willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
- Patent Title (中): 表现出von Willebrand因子（vWF）蛋白酶活性的组合物，其包含具有氨基酸序列AAGGILHLELLV的多肽链
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Application No.: US11166288Application Date: 2005-06-23
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Publication No.: US07501117B2Publication Date: 2009-03-10
- Inventor: Bernhard Laemmle , Helena Elisabeth Schaller-Gerritsen , Miha Furlan , Peter Turecek , Hans-Peter Schwarz , Friedrich Scheiflinger , Gerhard Antoine , Randolf Kerschbaumer , Luigina Tagliavacca , Klaus Zimmermann
- Applicant: Bernhard Laemmle , Helena Elisabeth Schaller-Gerritsen , Miha Furlan , Peter Turecek , Hans-Peter Schwarz , Friedrich Scheiflinger , Gerhard Antoine , Randolf Kerschbaumer , Luigina Tagliavacca , Klaus Zimmermann
- Applicant Address: AT Vienna
- Assignee: Baxter Innovations GmbH
- Current Assignee: Baxter Innovations GmbH
- Current Assignee Address: AT Vienna
- Agency: Townsend and Townsend and Crew LLP
- Main IPC: A61K35/14
- IPC: A61K35/14 ; A61K38/46 ; C12N9/64 ; C07H21/04
Abstract:
The invention relates to vWF cleaving entities having a molecular weight of 180 kD, 170 kD, 160 kD, 120 kD or 110 kD and an N-terminal amino acid sequence of AAGGILHLELLV, vWF cleaving complexes and methods for their production.
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