Invention Grant
- Patent Title: N-acylsulfonamide apoptosis promoters
- Patent Title (中): N-酰基磺酰胺凋亡启动子
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Application No.: US10820097Application Date: 2004-04-07
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Publication No.: US07504512B2Publication Date: 2009-03-17
- Inventor: David J. Augeri , Steven A. Baumeister , Milan Bruncko , Daniel A. Dickman , Hong Ding , Jurgen Dinges , Stephen W. Fesik , Philip J. Hajduk , Aaron R. Kunzer , William McClellan , David G. Nettesheim , Thorsten Oost , Andrew M. Petros , Saul H. Rosenberg , Wang Shen , Sheela A. Thomas , Xilu Wang , Michael D. Wendt
- Applicant: David J. Augeri , Steven A. Baumeister , Milan Bruncko , Daniel A. Dickman , Hong Ding , Jurgen Dinges , Stephen W. Fesik , Philip J. Hajduk , Aaron R. Kunzer , William McClellan , David G. Nettesheim , Thorsten Oost , Andrew M. Petros , Saul H. Rosenberg , Wang Shen , Sheela A. Thomas , Xilu Wang , Michael D. Wendt
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agent Patricia Coleman James
- Main IPC: C07C211/00
- IPC: C07C211/00 ; A61K31/445
Abstract:
N-Benzoyl arylsulfonamides having the formula are BCL-X1 inhibitors and are useful for promoting apoptosis. Also disclosed are BCL-X1 inhibiting compositions and methods of promoting apoptosis in a mammal.
Public/Granted literature
- US20040192681A1 N-acylsulfonamide apoptosis promoters Public/Granted day:2004-09-30
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