Invention Grant
- Patent Title: Diphenylimidazopyrimidines as inhibitors of β-secretase
- Patent Title (中): 二苯基咪唑并嘧啶作为β-分泌酶的抑制剂
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Application No.: US11332732Application Date: 2006-01-13
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Publication No.: US07563796B2Publication Date: 2009-07-21
- Inventor: Michael Sotirios Malamas , James Joseph Erdei , Iwan Suwandi Gunawan , Pawel Wojciech Nowak , Boyd Lynn Harrison
- Applicant: Michael Sotirios Malamas , James Joseph Erdei , Iwan Suwandi Gunawan , Pawel Wojciech Nowak , Boyd Lynn Harrison
- Applicant Address: US NJ Madison
- Assignee: Wyeth
- Current Assignee: Wyeth
- Current Assignee Address: US NJ Madison
- Agent Ram W. Sabnis; Scott K. Larsen; David R. Kurlandsky
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P25/28
Abstract:
The present invention provides an amino-imidazolone compound of formula I Also provided are compositions and methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles.
Public/Granted literature
- US20060160828A1 Amino-imidazolones for the inhibition of beta-secretase Public/Granted day:2006-07-20
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