Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US10961485Application Date: 2004-10-08
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Publication No.: US07598412B2Publication Date: 2009-10-06
- Inventor: Sara S. Hadida Ruah , Ashvani K. Singh , Mark T. Miller , Matthew Hamilton , Peter D. J. Grootenhuis
- Applicant: Sara S. Hadida Ruah , Ashvani K. Singh , Mark T. Miller , Matthew Hamilton , Peter D. J. Grootenhuis
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Vertex Pharmaceuticals Incorporated
- Agent Nancy K. Brennan; Kumar Govindaswamy
- Main IPC: C07C229/00
- IPC: C07C229/00 ; C07C233/00
Abstract:
The present invention provides compounds of Formula I useful as modulators of ABC transporter activity, or a pharmaceutically acceptable salt thereof, wherein RB, n, B, RC, RD, RE, A, and Z are described generally and in classes and subclasses below. The present invention also provides pharmaceutical compositions, methods and kits associated with Formula I, useful for as modulators, and for the treatments of disease and disease conditions associated with ABC transporter proteins.
Public/Granted literature
- US20050148648A1 Modulators of ATP-binding cassette transporters Public/Granted day:2005-07-07
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