发明授权
- 专利标题： Modulators of ATP-binding cassette transporters
- 专利标题（中）： ATP结合盒转运蛋白的调节剂
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申请号： US10961485申请日： 2004-10-08
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公开(公告)号： US07598412B2公开(公告)日： 2009-10-06
- 发明人: Sara S. Hadida Ruah , Ashvani K. Singh , Mark T. Miller , Matthew Hamilton , Peter D. J. Grootenhuis
- 申请人： Sara S. Hadida Ruah , Ashvani K. Singh , Mark T. Miller , Matthew Hamilton , Peter D. J. Grootenhuis
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理机构： Vertex Pharmaceuticals Incorporated
- 代理商 Nancy K. Brennan; Kumar Govindaswamy
- 主分类号： C07C229/00
- IPC分类号： C07C229/00 ; C07C233/00
摘要：
The present invention provides compounds of Formula I useful as modulators of ABC transporter activity, or a pharmaceutically acceptable salt thereof, wherein RB, n, B, RC, RD, RE, A, and Z are described generally and in classes and subclasses below. The present invention also provides pharmaceutical compositions, methods and kits associated with Formula I, useful for as modulators, and for the treatments of disease and disease conditions associated with ABC transporter proteins.
公开/授权文献
- US20050148648A1 Modulators of ATP-binding cassette transporters 公开/授权日：2005-07-07
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