发明授权
- 专利标题： Development and use of fluorescent probes of unbound analytes
- 专利标题（中）： 开发和使用未结合的分析物的荧光探针
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申请号： US11085792申请日： 2005-03-21
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公开(公告)号： US07601510B2公开(公告)日： 2009-10-13
- 发明人: Alan Marc Kleinfeld , Andrew Henry Huber , James Patrick Kampf , Thomas Kwan , Baolong Zhu
- 申请人： Alan Marc Kleinfeld , Andrew Henry Huber , James Patrick Kampf , Thomas Kwan , Baolong Zhu
- 申请人地址： US CA San Diego
- 专利权人： FFA Sciences LLC
- 当前专利权人： FFA Sciences LLC
- 当前专利权人地址： US CA San Diego
- 代理机构： Knobbe, Martens, Olson & Bear, LLP
- 主分类号： G01N33/567
- IPC分类号： G01N33/567 ; G01N33/543 ; G01N33/44 ; C07K14/00
摘要：
A method for high throughput screening of probes is described. These probes are useful for characterization and measurement of unbound metabolites in a fluid sample, particularly characterization and measurement of levels of unbound free fatty acids. By practice of the disclosed invention, a profile of unbound metabolites can be determined for an individual which can be used to determine the individual's relative risk for disease such as stroke, cardiac disease and cancer.
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