发明授权
- 专利标题: N-substituted glycine derivatives: hydroxylase inhibitors
- 专利标题(中): N-取代的甘氨酸衍生物:羟化酶抑制剂
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申请号: US11972702申请日: 2008-01-11
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公开(公告)号: US07608621B2公开(公告)日: 2009-10-27
- 发明人: Antony N. Shaw , Kevin J. Duffy , William Henry Miller , Andrea K. Myers , Michael N. Zimmerman
- 申请人: Antony N. Shaw , Kevin J. Duffy , William Henry Miller , Andrea K. Myers , Michael N. Zimmerman
- 申请人地址: US PA Philadelphia
- 专利权人: SmithKline Beecham, Corp.
- 当前专利权人: SmithKline Beecham, Corp.
- 当前专利权人地址: US PA Philadelphia
- 代理商 James M. Kanagy; Edward R. Gimmi; Charles M. Kinzig
- 主分类号: A61K31/501
- IPC分类号: A61K31/501 ; C07D237/04 ; C07D401/10 ; C07D403/04 ; C07D403/10 ; C07D405/04 ; C07D405/10 ; C07D409/04 ; C07D409/10 ; C07C229/22 ; C07C229/38 ; C07C229/40 ; C07C229/46 ; A61P7/06 ; C07F401/04
摘要:
The invention described herein relates to certain pyridazinedione N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.