发明授权
US07622605B2 Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
失效
丙型肝炎病毒RNA依赖性RNA聚合酶的抑制剂,以及使用其的组合物和治疗
- 专利标题: Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same
- 专利标题(中): 丙型肝炎病毒RNA依赖性RNA聚合酶的抑制剂,以及使用其的组合物和治疗
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申请号: US11470540申请日: 2006-09-06
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公开(公告)号: US07622605B2公开(公告)日: 2009-11-24
- 发明人: Javier Gonzalez , Tanya Michelle Jewell , Hui Li , Angelica Linton , John Howard Tatlock
- 申请人: Javier Gonzalez , Tanya Michelle Jewell , Hui Li , Angelica Linton , John Howard Tatlock
- 申请人地址: US NY New York
- 专利权人: Pfizer Inc.
- 当前专利权人: Pfizer Inc.
- 当前专利权人地址: US NY New York
- 代理商 Gregg C. Benson; B. Timothy Creagan
- 主分类号: C07C69/34
- IPC分类号: C07C69/34 ; C07C69/52
摘要:
The present invention provides compounds of formula (4), and their pharmaceutically acceptable salts and solvates, which are useful as inhibitors of the Hepatitis C virus (HCV) polymerase enzyme and are also useful for the treatment of HCV infections in HCV-infected mammals. The present invention also provides pharmaceutical compositions comprising compounds of formula (4), their pharmaceutically acceptable salts and solvates. Furthermore, the present invention provides intermediate compounds and methods useful in the preparation of compounds of formula (4).
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