发明授权
US07635715B2 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
有权
显示脯氨酰羟化酶抑制活性的萘环酮化合物,组合物和用途
- 专利标题: Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
- 专利标题(中): 显示脯氨酰羟化酶抑制活性的萘环酮化合物,组合物和用途
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申请号: US12002537申请日: 2007-12-17
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公开(公告)号: US07635715B2公开(公告)日: 2009-12-22
- 发明人: Jennifer R. Allen , Kaustav Biswas , Marian C. Bryan , Roland Burli , Guo-Qiang Cao , Michael J. Frohn , Jennifer E. Golden , Stephanie Mercede , Susana Neira , Tanya Peterkin , Alexander J. Pickrell , Anthony Reed , Christopher M. Tegley , Xiang Wang
- 申请人: Jennifer R. Allen , Kaustav Biswas , Marian C. Bryan , Roland Burli , Guo-Qiang Cao , Michael J. Frohn , Jennifer E. Golden , Stephanie Mercede , Susana Neira , Tanya Peterkin , Alexander J. Pickrell , Anthony Reed , Christopher M. Tegley , Xiang Wang
- 申请人地址: US CA Thousand Oaks
- 专利权人: Amgen Inc.
- 当前专利权人: Amgen Inc.
- 当前专利权人地址: US CA Thousand Oaks
- 代理商 Bernard Friedrichsen
- 主分类号: A61K31/352
- IPC分类号: A61K31/352 ; C07D311/96
摘要:
Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
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