发明授权
- 专利标题: Methods for the specific preparation of lysobactin fragments
- 专利标题(中): 溶菌球蛋白片段的具体制备方法
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申请号: US11800102申请日: 2007-05-04
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公开(公告)号: US07737120B2公开(公告)日: 2010-06-15
- 发明人: Franz Von Nussbaum , Werner Schroeder , Chantal Fuerstner
- 申请人: Franz Von Nussbaum , Werner Schroeder , Chantal Fuerstner
- 申请人地址: DE Wuppertal
- 专利权人: Aicuris GmbH & Co. KG
- 当前专利权人: Aicuris GmbH & Co. KG
- 当前专利权人地址: DE Wuppertal
- 代理机构: Morrison & Foerster LLP
- 优先权: DE102004053409 20041105
- 主分类号: A61K38/08
- IPC分类号: A61K38/08 ; A61K38/48
摘要:
The invention relates to methods for the targeted production of lysobactin derivatives by combined chemical and enzymatic modifications. In particular, the invention relates to method for preparing lysobactin fragment 4-11 by chemical reduction and cleavage of the resultant product by chymotrypsin.
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