发明授权
- 专利标题： Anti-human DLL4 antibodies and compositions
- 专利标题（中）： 抗人DLL4抗体和组合物
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申请号： US11905392申请日： 2007-09-28
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公开(公告)号： US07750124B2公开(公告)日： 2010-07-06
- 发明人: Austin Gurney , Fumiko Axelrod , Tim Hoey , Sanjeev Satyal
- 申请人： Austin Gurney , Fumiko Axelrod , Tim Hoey , Sanjeev Satyal
- 申请人地址： US CA Redwood City
- 专利权人： OncoMed Pharmaceuticals, Inc.
- 当前专利权人： OncoMed Pharmaceuticals, Inc.
- 当前专利权人地址： US CA Redwood City
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 主分类号： C12P21/08
- IPC分类号： C12P21/08 ; C07K16/00 ; A61K39/395 ; C12P21/04
摘要：
An isolated antibody that specifically binds to an extracellular domain of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a method of treating cancer comprising administering a therapeutically effective amount of an anti-DLL4 antibody.
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