发明授权
US07763431B1 Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
有权
使用T1R2 / T1R3(甜味)味觉受体的结合测定法鉴定引起或调节甜味的化合物
- 专利标题: Binding assays that use the T1R2/T1R3 (sweet) taste receptor to identify compounds that elicit or modulate sweet taste
- 专利标题(中): 使用T1R2 / T1R3(甜味)味觉受体的结合测定法鉴定引起或调节甜味的化合物
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申请号: US10725076申请日: 2003-12-02
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公开(公告)号: US07763431B1公开(公告)日: 2010-07-27
- 发明人: Mark Zoller , Xiaodong Li , Lena Staszewski , Shawn O'Connell , Sergey Zozulya , Jon Elliot Adler , Hong Xu , Fernando Echeverri
- 申请人: Mark Zoller , Xiaodong Li , Lena Staszewski , Shawn O'Connell , Sergey Zozulya , Jon Elliot Adler , Hong Xu , Fernando Echeverri
- 申请人地址: US CA San Diego
- 专利权人: Senomyx, Inc.
- 当前专利权人: Senomyx, Inc.
- 当前专利权人地址: US CA San Diego
- 代理机构: Hunton & Williams LLP
- 主分类号: G01N33/53
- IPC分类号: G01N33/53 ; G01N33/567 ; C12P21/06 ; C12N1/20 ; C12N15/74 ; C12N15/00 ; C12N15/02 ; C07K1/00 ; C07K14/00 ; C07K17/00 ; C07H21/04
摘要:
Binding assays for identifying compounds that induce or modulate the T1R2/T1R3 (sweet) receptor associated taste are provided. These binding assays detect the specific binding or a component to a T1R2/T1R3 (sweet) taste receptor or detect modulation (inhibition or enhancement) of the binding of another compound, e.g., saccharin or another sweetener to a T1R2/T1R3 (sweet) taste receptor. Compounds that are identified in these binding assays have potential application of T1R2/T1R3 sweet taste receptor modulators and can be used as flavor additives in compositions for human or animal consumption.
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