发明授权
- 专利标题： Reagent for fluorimetric determination of analytes
- 专利标题（中）： 用于荧光测定分析物的试剂
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申请号： US12107116申请日： 2008-04-22
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公开(公告)号： US07807402B2公开(公告)日： 2010-10-05
- 发明人: Carina Horn , Hans-Peter Josel , Juergen Spinke , Rupert Herrmann , Dieter Heindl
- 申请人： Carina Horn , Hans-Peter Josel , Juergen Spinke , Rupert Herrmann , Dieter Heindl
- 申请人地址： US IN Indianapolis
- 专利权人： Roche Diagnostics Operations, Inc.
- 当前专利权人： Roche Diagnostics Operations, Inc.
- 当前专利权人地址： US IN Indianapolis
- 代理机构： McDonnell Boehnen Hulbert & Berghoff, LLP
- 优先权： DE10303265 20030128
- 主分类号： C12Q1/26
- IPC分类号： C12Q1/26
摘要：
A method and reagent for detecting the presence or amount of an analyte by a redox reaction and a fluorimetric determination, is disclosed. The reagent comprises a compound of the general formula Q-F as a redox indicator, wherein Q is a quencher group and F is a fluorophore group. The quencher group Q or/and the fluorophore group F can be reduced or oxidized, and the fluorescence can change depending on the reduction or oxidation.