Invention Grant
US07888118B2 2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole and methods for inducing differentiation of myoblasts or muscle fibers into neuron cells
有权
2- {2- [5-（3-氯苯基）]呋喃基} -4,5-双（4-甲氧基苯基）咪唑和诱导成肌细胞或肌纤维分化成神经元细胞的方法
![2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole and methods for inducing differentiation of myoblasts or muscle fibers into neuron cells](/docs/US/2011-02-15/US07888118B2/abs.jpg.600x600.jpg)
- Patent Title: 2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole and methods for inducing differentiation of myoblasts or muscle fibers into neuron cells
- Patent Title (中): 2- {2- [5-（3-氯苯基）]呋喃基} -4,5-双（4-甲氧基苯基）咪唑和诱导成肌细胞或肌纤维分化成神经元细胞的方法
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Application No.: US12749922Application Date: 2010-03-30
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Publication No.: US07888118B2Publication Date: 2011-02-15
- Inventor: In-Jae Shin , Myung-Ryul Lee , Darren Williams
- Applicant: In-Jae Shin , Myung-Ryul Lee , Darren Williams
- Applicant Address: KR
- Assignee: Industry-Academic Cooperation Foundation, Yonsei University
- Current Assignee: Industry-Academic Cooperation Foundation, Yonsei University
- Current Assignee Address: KR
- Agency: Cantor Colburn LLP
- Priority: KR10-2005-0113315 20051125
- Main IPC: C12N5/00
- IPC: C12N5/00
![2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole and methods for inducing differentiation of myoblasts or muscle fibers into neuron cells](/abs-image/US/2011/02/15/US07888118B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to 4,5-bis(4-methoxyphenyl)imidazole compound inducing differentiation of myoblasts or muscle fibers into neuron cells, a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation. More specifically, it relates to 2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole that induces differentiation of myoblasts or muscle fibers into neuron cells, all pharmaceutically acceptable isomers, salts, and a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation.
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