Invention Grant
US07928139B2 Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
有权
显示脯氨酰羟化酶抑制活性的萘环酮化合物，组合物和用途
- Patent Title: Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof
- Patent Title (中): 显示脯氨酰羟化酶抑制活性的萘环酮化合物，组合物和用途
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Application No.: US12612465Application Date: 2009-11-04
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Publication No.: US07928139B2Publication Date: 2011-04-19
- Inventor: Jennifer R. Allen , Kaustav Biswas , Marian C. Bryan , Roland Burli , Guo-Qiang Cao , Michael J. Frohn , Jennifer E. Golden , Stephanie Mercede , Susana Neira , Tanya Peterkin , Alexander J. Pickrell , Anthony Reed , Christopher M. Tegley , Xiang Wang
- Applicant: Jennifer R. Allen , Kaustav Biswas , Marian C. Bryan , Roland Burli , Guo-Qiang Cao , Michael J. Frohn , Jennifer E. Golden , Stephanie Mercede , Susana Neira , Tanya Peterkin , Alexander J. Pickrell , Anthony Reed , Christopher M. Tegley , Xiang Wang
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Bernard P. Friedrichsen
- Main IPC: A61K31/352
- IPC: A61K31/352 ; A61K31/195
Abstract:
Compounds of Formula I and Formula II are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula I and Formula II have the following structures: where the definitions of the variables are provided herein.
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