发明授权
- 专利标题： Membrane arrays and methods of manufacture
- 专利标题（中）： 膜阵列和制造方法
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申请号： US12330660申请日： 2008-12-09
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公开(公告)号： US07939341B2公开(公告)日： 2011-05-10
- 发明人: Alain R.E. Carre , Alexander M. Efremov , Ye Fang , Yulong Hong , Valerie Lacarriere , Joydeep Lahiri , Fang Lai , John C. Mauro , Srikanth Raghavan , Brian L. Webb
- 申请人： Alain R.E. Carre , Alexander M. Efremov , Ye Fang , Yulong Hong , Valerie Lacarriere , Joydeep Lahiri , Fang Lai , John C. Mauro , Srikanth Raghavan , Brian L. Webb
- 申请人地址： US NY Corning
- 专利权人： Corning Incorporated
- 当前专利权人： Corning Incorporated
- 当前专利权人地址： US NY Corning
- 代理商 John L. Beck
- 主分类号： G01N33/566
- IPC分类号： G01N33/566
摘要：
The invention relates to G protein-coupled receptor (GPCR) microarrays on porous substrates for structural or functional analyses of GPCRs, and methods of preparing porous substrate surfaces for receiving membranes that comprise GPCRs. In one embodiment, a GPCR microarray of the invention comprises a membrane adhered to an upper surface of a porous substrate, the membrane spanning across a plurality of pores on the porous substrate to form a plurality of cavities having sufficient geometry to permit entry of assay reagents into each cavity, thereby allowing access of assay reagents to both sides of GPCR in the membrane.
公开/授权文献
- US20090093371A1 MEMBRANE ARRAYS AND METHODS OF MANUFACTURE 公开/授权日：2009-04-09
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