发明授权
US07956173B2 Nucleic acids coding for humanized antibodies for binding sphingosine-1-phosphate
有权
编码用于结合鞘氨醇-1-磷酸的人源化抗体的核酸
- 专利标题: Nucleic acids coding for humanized antibodies for binding sphingosine-1-phosphate
- 专利标题(中): 编码用于结合鞘氨醇-1-磷酸的人源化抗体的核酸
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申请号: US12258353申请日: 2008-10-24
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公开(公告)号: US07956173B2公开(公告)日: 2011-06-07
- 发明人: Roger A. Sabbadini , William A. Garland , Genevieve Hansen , Steven Tarran Jones , David Gareth Williams
- 申请人: Roger A. Sabbadini , William A. Garland , Genevieve Hansen , Steven Tarran Jones , David Gareth Williams
- 申请人地址: US CA San Diego
- 专利权人: Lpath, Inc.
- 当前专利权人: Lpath, Inc.
- 当前专利权人地址: US CA San Diego
- 代理机构: BioTechnology Law Group
- 代理商 Daniel M. Chambers
- 主分类号: C07H21/04
- IPC分类号: C07H21/04 ; C07K16/00 ; C12P21/08 ; A61K39/395 ; A61K39/00
摘要:
The present invention relates to anti-S1P agents, particularly humanized monoclonal antibodies (and antigen binding fragments thereof) specifically reactive with S1P, compositions containing such antibodies (or fragments), and the use of such antibodies (or fragments), for example, to treat diseases and conditions associated with aberrant levels of S1P.
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