Invention Grant
US07968316B2 Method for the mass production of immunoglobulin Fc region deleted initial methionine residues
有权
大量生产免疫球蛋白Fc区缺失的初始甲硫氨酸残基的方法
- Patent Title: Method for the mass production of immunoglobulin Fc region deleted initial methionine residues
- Patent Title (中): 大量生产免疫球蛋白Fc区缺失的初始甲硫氨酸残基的方法
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Application No.: US12063379Application Date: 2006-08-16
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Publication No.: US07968316B2Publication Date: 2011-06-28
- Inventor: Sung youb Jung , Jin Sun Kim , Jin hwan Shin , Se-Chang Kwon , Gwan-Sun Lee , Dae hae Song
- Applicant: Sung youb Jung , Jin Sun Kim , Jin hwan Shin , Se-Chang Kwon , Gwan-Sun Lee , Dae hae Song
- Applicant Address: KR Seoul
- Assignee: Hanmi Holdings Co., Ltd.
- Current Assignee: Hanmi Holdings Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2005-0074989 20050816
- International Application: PCT/KR2006/003207 WO 20060816
- International Announcement: WO2007/021129 WO 20070222
- Main IPC: C12P21/04
- IPC: C12P21/04 ; C12N15/64 ; C12N15/00 ; C07H21/04
Abstract:
Disclosed is a method for the mass production of a monomeric or dimeric immunoglobulin Fc region, free of initial methionine residues, using a recombinant expression vector comprising a nucleotide sequence coding for a recombinant immunoglobulin Fc region comprising an immunoglobulin Fc region linked at the N-terminus thereof to an immunoglobulin Fc region via a peptide bond.
Public/Granted literature
- US20080293106A1 Method For the Mass Production of Immunoglobulin Fc Region Deleted Initial Methionine Residues Public/Granted day:2008-11-27
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