发明授权
US08088610B2 Ketoreductases for the production of (S,E)-methyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-hroxypropyl)benzoate
有权
用于生产（S，E）-2-（3-（3-（2-（7-氯喹啉-2-基）乙烯基）苯基）-3-羟基丙基）苯甲酸甲酯的酮还原酶
- 专利标题： Ketoreductases for the production of (S,E)-methyl 2-(3-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-hroxypropyl)benzoate
- 专利标题（中）： 用于生产（S，E）-2-（3-（3-（2-（7-氯喹啉-2-基）乙烯基）苯基）-3-羟基丙基）苯甲酸甲酯的酮还原酶
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申请号： US12240986申请日： 2008-09-29
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公开(公告)号： US08088610B2公开(公告)日： 2012-01-03
- 发明人: Jack Liang , Birthe Borup , Vesna Mitchell , Emily Mundorff , James LaLonde , Gjalt W. Huisman
- 申请人： Jack Liang , Birthe Borup , Vesna Mitchell , Emily Mundorff , James LaLonde , Gjalt W. Huisman
- 申请人地址： US CA Redwood City
- 专利权人： Codexis, Inc.
- 当前专利权人： Codexis, Inc.
- 当前专利权人地址： US CA Redwood City
- 主分类号： C12N9/00
- IPC分类号： C12N9/00 ; C12N9/04 ; C12N1/20 ; C12N15/00 ; C07H21/04
摘要：
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
公开/授权文献
- US20090155863A1 KETOREDUCTASE POLYPEPTIDES AND USES THEREOF 公开/授权日：2009-06-18
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