Invention Grant
US08115016B2 Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid
有权
制备5-联苯-4-氨基-2-甲基戊酸的方法
- Patent Title: Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid
- Patent Title (中): 制备5-联苯-4-氨基-2-甲基戊酸的方法
-
Application No.: US12522767Application Date: 2008-01-10
-
Publication No.: US08115016B2Publication Date: 2012-02-14
- Inventor: David Hook , Thomas Ruch , Bernhard Riss , Bernhard Wietfeld , Gottfried Sedelmeier , Matthias Napp , Markus Bänziger , Steven Hawker , Lech Ciszewski , Liladhar M Waykole
- Applicant: David Hook , Thomas Ruch , Bernhard Riss , Bernhard Wietfeld , Gottfried Sedelmeier , Matthias Napp , Markus Bänziger , Steven Hawker , Lech Ciszewski , Liladhar M Waykole
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Stephen E. Johnson
- Priority: EP07100451 20070112
- International Application: PCT/EP2008/000142 WO 20080110
- International Announcement: WO2008/083967 WO 20080717
- Main IPC: C07D207/26
- IPC: C07D207/26 ; C07D207/27 ; C07D207/263 ; C07D207/267 ; C07F7/10
Abstract:
The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1-oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R)-methyl butanoic acid ethyl ester or salt thereof.
Public/Granted literature
- US20100113801A1 Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid Public/Granted day:2010-05-06
Information query
