Invention Grant
- Patent Title: Bicyclic and tricyclic compounds as KAT II inhibitors
- Patent Title (中): 双环和三环化合物作为KAT II抑制剂
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Application No.: US12816612Application Date: 2010-06-16
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Publication No.: US08183238B2Publication Date: 2012-05-22
- Inventor: Michelle M. Claffey , Amy B. Dounay , Matthew M. Hayward , Suobao Rong , Patrick R. Verhoest , Jamison B. Tuttle , Xinmin Gan
- Applicant: Michelle M. Claffey , Amy B. Dounay , Matthew M. Hayward , Suobao Rong , Patrick R. Verhoest , Jamison B. Tuttle , Xinmin Gan
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Feng Shao
- Main IPC: A61K31/52
- IPC: A61K31/52 ; A61K31/519 ; A61K31/5377 ; A61K31/4375 ; A61K31/473 ; A61K31/4741 ; A61K31/506 ; A61K31/501 ; A61K31/517 ; C07D473/30 ; C07D473/20 ; C07D413/12 ; C07D405/10 ; C07D401/10 ; C07D401/04 ; C07D471/04 ; C07D215/58 ; C07D221/10 ; C07D413/10 ; C07D491/048 ; C07D487/04
Abstract:
Compounds of Formula X: wherein A, X, Y, Z, R5, R6a, and R6b are as defined herein, and pharmaceutically acceptable salts thereof, are described as useful for the treatment of cognitive deficits associated with schizophrenia and other neurodegenerative and/or neurological disorders in mammals, including humans.
Public/Granted literature
- US20100324043A1 Bicyclic And Tricyclic Compounds As KAT II Inhibitors Public/Granted day:2010-12-23
Information query
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