Invention Grant
US08198298B2 Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors
有权
作为激酶抑制剂活性的吡咯并[2,3-b]吡啶衍生物
![Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors](/docs/US/2012-06-12/US08198298B2/abs.jpg.600x600.jpg)
- Patent Title: Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors
- Patent Title (中): 作为激酶抑制剂活性的吡咯并[2,3-b]吡啶衍生物
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Application No.: US13026789Application Date: 2011-02-14
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Publication No.: US08198298B2Publication Date: 2012-06-12
- Inventor: Barbara Salom , Matteo D'Anello , Maria Gabriella Brasca , Patrizia Giordano , Katia Martina , Dania Tesei , Frederick Arthur Brookfield , William John Trigg , Edward Andrew Boyd , Jonathan Anthony Larard
- Applicant: Barbara Salom , Matteo D'Anello , Maria Gabriella Brasca , Patrizia Giordano , Katia Martina , Dania Tesei , Frederick Arthur Brookfield , William John Trigg , Edward Andrew Boyd , Jonathan Anthony Larard
- Applicant Address: IT Rome
- Assignee: Pfizer Italia S.r.l.
- Current Assignee: Pfizer Italia S.r.l.
- Current Assignee Address: IT Rome
- Agency: Scully, Scott, Murphy & Presser, P.C.
- Priority: GB0330042.3 20031224
- Main IPC: A61K31/44
- IPC: A61K31/44
![Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors](/abs-image/US/2012/06/12/US08198298B2/abs.jpg.150x150.jpg)
Abstract:
Compounds which are pyrrolo[2,3-b]pyridine derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, cell proliferative disorders, Alzheimer's disease, viral infections, auto-immune diseases and neurodegenerative disorders; also disclosed is a process under SPS conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.
Public/Granted literature
- US20110136857A1 PYRROLE[2,3-B]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS Public/Granted day:2011-06-09
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