发明授权
- 专利标题: Macrocyclic compounds and methods of making and using the same
- 专利标题(中): 大环化合物及其制备和使用方法
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申请号: US10590782申请日: 2005-02-25
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公开(公告)号: US08202843B2公开(公告)日: 2012-06-19
- 发明人: Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
- 申请人: Jay J. Farmer , Ashoke Bhattacharjee , Yi Chen , Joel A. Goldberg , Joseph A. Ippolito , Zoltan F. Kanyo , Rongliang Lou , Adegboyega K. Oyelere , Edward C. Sherer , Joyce A. Sutcliffe , Deping Wang , Yusheng Wu , Yanming Du
- 申请人地址: US CT New Haven
- 专利权人: Rib-X Pharmaceuticals, Inc.
- 当前专利权人: Rib-X Pharmaceuticals, Inc.
- 当前专利权人地址: US CT New Haven
- 代理机构: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- 代理商 Ivor R. Elrifi, Esq.; Jennifer L. Loebach
- 国际申请: PCT/US2005/006082 WO 20050225
- 国际公布: WO2005/085266 WO 20050915
- 主分类号: A61K31/70
- IPC分类号: A61K31/70 ; C07H17/08
摘要:
The present invention provides macrocyclic compounds useful as therapeutic agents of the formula: or a pharmaceutically acceptable salt, ester, N-oxide, or prodrug thereof, wherein T, R1, R2, R3, D, E, F, and G are as defined herein. More particularly, these compounds are useful as anti-infective, antiproliferative, anti-inflammatory and prokinetic agents.
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