Invention Grant
US08278442B2 Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
失效
用于治疗代谢紊乱的双环芳基和杂芳基化合物
- Patent Title: Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
- Patent Title (中): 用于治疗代谢紊乱的双环芳基和杂芳基化合物
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Application No.: US12601100Application Date: 2008-05-22
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Publication No.: US08278442B2Publication Date: 2012-10-02
- Inventor: Jason Bloxham , Stuart Edward Bradley , Tom Banksia Dupree , Peter Timothy Fry , Patrick Eric Hanrahan , Thomas Martin Krulle , Martin James Procter , Colin Peter Sambrook-Smith , Karen Lesley Schofield , Donald Smyth , Alan John Stewart
- Applicant: Jason Bloxham , Stuart Edward Bradley , Tom Banksia Dupree , Peter Timothy Fry , Patrick Eric Hanrahan , Thomas Martin Krulle , Martin James Procter , Colin Peter Sambrook-Smith , Karen Lesley Schofield , Donald Smyth , Alan John Stewart
- Applicant Address: GB Oxford
- Assignee: Prosidion Limited
- Current Assignee: Prosidion Limited
- Current Assignee Address: GB Oxford
- Agency: Mintz Levin Cohn Ferris Glovsky and Popeo, P.C.
- Agent Ivor R. Elrifi; Heidi A. Erlacher
- Priority: GB0709789.2 20070522; GB0800454.1 20080111
- International Application: PCT/GB2008/050370 WO 20080522
- International Announcement: WO2008/142454 WO 20081127
- Main IPC: C07D213/84
- IPC: C07D213/84 ; C07D217/22 ; C07D403/12 ; C07D413/12
Abstract:
Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.
Public/Granted literature
- US20100173886A1 BICYCLIC ARYL AND HETEROARYL COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS Public/Granted day:2010-07-08
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