Invention Grant
- Patent Title: Inhibitors of cytosolic phospholipase A2
- Patent Title (中): 胞浆磷脂酶A2抑制剂
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Application No.: US12488182Application Date: 2009-06-19
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Publication No.: US08283373B2Publication Date: 2012-10-09
- Inventor: John C. McKew , Katherine L. Lee , Lihren Chen , Richard Vargas , James D. Clark , Cara Williams , Valerie Clerin , Suzana Marusic , Kevin Pong
- Applicant: John C. McKew , Katherine L. Lee , Lihren Chen , Richard Vargas , James D. Clark , Cara Williams , Valerie Clerin , Suzana Marusic , Kevin Pong
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent Richard V. Zanzalari
- Main IPC: A61K31/404
- IPC: A61K31/404
Abstract:
This invention provides chemical inhibitors of the activity of various phospholipase enzymes, particularly cytosolic phospholipase A2 enzymes (cPLA2), more particularly including inhibitors of cytosolic phospholipase A2 alpha enzymes (cPLA2α). In some embodiments, the inhibitors have the Formula I: wherein the constituent variables are as defined herein.
Public/Granted literature
- US20100022536A1 Inhibitors of Cytosolic Phospholipase A2 Public/Granted day:2010-01-28
Information query
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