Invention Grant
- Patent Title: Substituted bicyclic pyrimidines
- Patent Title (中): 取代的双环嘧啶
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Application No.: US12939527Application Date: 2010-11-04
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Publication No.: US08354414B2Publication Date: 2013-01-15
- Inventor: Edward R. Bacon , Thomas Bailey , Nadine C. Becknell , Diane E. Gingrich , Greg A. Hostetler , Robert L. Hudkins , Keith S. Learn , Jason C. Wagner
- Applicant: Edward R. Bacon , Thomas Bailey , Nadine C. Becknell , Diane E. Gingrich , Greg A. Hostetler , Robert L. Hudkins , Keith S. Learn , Jason C. Wagner
- Applicant Address: US PA Frazer
- Assignee: Cephalon, Inc
- Current Assignee: Cephalon, Inc
- Current Assignee Address: US PA Frazer
- Main IPC: C07D239/70
- IPC: C07D239/70 ; C07D471/04 ; A61K31/517 ; A61K31/519 ; C07D239/72 ; C07D239/84 ; C07D239/78 ; C07D487/04
Abstract:
The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions that include substituted heterobicyclic pyrimidines of Formula (I): wherein R1, R2, R3, R4, R5, X, W, and ring A are as defined herein; pharmaceutical compositions of substituted heterobicyclic pyrimidines of Formula (I); and their use in the treatment of chronic neurodegenerative diseases, neurotraumatic diseases, depression and/or diabetes. More particularly, the present invention relates to substituted pyrazolopyrimidines of Formula (I).
Public/Granted literature
- US20110053920A1 SUBSTITUTED BICYCLIC PYRIMIDINES Public/Granted day:2011-03-03
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