发明授权
- 专利标题： Benzimidazole analogues for the treatment or prevention of flavivirus infections
- 专利标题（中）： 苯并咪唑类似物用于治疗或预防黄病毒感染
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申请号： US12838350申请日： 2010-07-16
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公开(公告)号： US08354419B2公开(公告)日： 2013-01-15
- 发明人: James A. Henderson , John Maxwell , Louis Vaillancourt , Mark Morris , Ronald Grey, Jr. , Simon Giroux , Laval Chan Chun Kong , Sanjoy Kumar Das , Bingcan Liu , Carl Poisson , Caroline Cadilhac , Monica Bubenik , T. Jagadeeswar Reddy , Guy Falardeau , Constantin Yannopoulos , Jian Wang , Oswy Z. Pereira , Youssef L. Bennani , Albert C. Pierce , Govinda Rao Bhisetti , Kevin M. Cottrell , Valerie Marone
- 申请人： James A. Henderson , John Maxwell , Louis Vaillancourt , Mark Morris , Ronald Grey, Jr. , Simon Giroux , Laval Chan Chun Kong , Sanjoy Kumar Das , Bingcan Liu , Carl Poisson , Caroline Cadilhac , Monica Bubenik , T. Jagadeeswar Reddy , Guy Falardeau , Constantin Yannopoulos , Jian Wang , Oswy Z. Pereira , Youssef L. Bennani , Albert C. Pierce , Govinda Rao Bhisetti , Kevin M. Cottrell , Valerie Marone
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理商 Lisa A. Dixon; Susan C. Kelly
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K31/4439 ; A61K31/4184 ; C07D403/14 ; C07D401/14
摘要：
Compounds represented by formula I: or pharmaceutically acceptable salts and solvates thereof, wherein A, B, B′, X, Y, R1, R1′, R2, R2′, R3, R3′, R5, R5′, R6, m, n, or p are as defined herein, are useful for treating flaviviridae viral infections.
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