Invention Grant
US08383767B2 Immunogenic protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain
有权
含有抗原呈递细胞结合结构域和富含半胱氨酸的结构域的免疫原性蛋白载体
- Patent Title: Immunogenic protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain
- Patent Title (中): 含有抗原呈递细胞结合结构域和富含半胱氨酸的结构域的免疫原性蛋白载体
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Application No.: US12491521Application Date: 2009-06-25
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Publication No.: US08383767B2Publication Date: 2013-02-26
- Inventor: Jaulang Hwang , Chun-Cheng Lin , Hsiao-Ling Chiang , Fan-Dan Jan , Chiao-En Chen , Chia-Tse Shu
- Applicant: Jaulang Hwang , Chun-Cheng Lin , Hsiao-Ling Chiang , Fan-Dan Jan , Chiao-En Chen , Chia-Tse Shu
- Applicant Address: TW Taipei
- Assignee: Academia Sinica
- Current Assignee: Academia Sinica
- Current Assignee Address: TW Taipei
- Agency: Occhiuti Rohlicek & Tsao LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K39/00 ; A61K39/38 ; A61K45/00 ; A61K47/00 ; C07K2/00 ; C07K4/00 ; C07K5/00 ; C07K7/00 ; C07K14/00 ; C07K16/00
Abstract:
A protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain. Also described herein is an immunoconjugate containing the protein carrier with an antigen conjugated to multiple cysteine residues in the cysteine-rich domain, and an immune composition containing the immunoconjugate and an adjuvant, as well as their uses in eliciting immune responses.
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