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1.发明授权Immunogenic protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain 有权含有抗原呈递细胞结合结构域和富含半胱氨酸的结构域的免疫原性蛋白载体公开(公告)号：US08383767B2
公开(公告)日：2013-02-26
申请号：US12491521
申请日：2009-06-25
Applicant: Jaulang Hwang , Chun-Cheng Lin , Hsiao-Ling Chiang , Fan-Dan Jan , Chiao-En Chen , Chia-Tse Shu
Inventor： Jaulang Hwang , Chun-Cheng Lin , Hsiao-Ling Chiang , Fan-Dan Jan , Chiao-En Chen , Chia-Tse Shu
IPC: A61K38/00 , A61K39/00 , A61K39/38 , A61K45/00 , A61K47/00 , C07K2/00 , C07K4/00 , C07K5/00 , C07K7/00 , C07K14/00 , C07K16/00
CPC classification number: C07K14/21 , A61K39/00 , A61K39/0011 , C07K14/28 , C07K14/33 , C07K16/3076 , C07K16/3084 , C07K2319/30 , C07K2319/55 , Y02A50/472
Abstract: A protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain. Also described herein is an immunoconjugate containing the protein carrier with an antigen conjugated to multiple cysteine residues in the cysteine-rich domain, and an immune composition containing the immunoconjugate and an adjuvant, as well as their uses in eliciting immune responses.
Abstract translation: 含有抗原呈递细胞结合结构域和富含半胱氨酸的结构域的蛋白质载体。 本文还描述了含有具有与富含半胱氨酸的结构域中的多个半胱氨酸残基缀合的抗原的蛋白质载体的免疫缀合物，以及含有免疫缀合物和佐剂的免疫组合物，以及它们在引发免疫应答中的用途。
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2.发明申请Immunogenic Protein Carrier Containing An Antigen Presenting Cell Binding Domain and A Cysteine-Rich Domain 有权包含抗原呈递细胞结合域和富含半胱氨酸的结构域的免疫原性蛋白载体公开(公告)号：US20090324619A1
公开(公告)日：2009-12-31
申请号：US12491521
申请日：2009-06-25
Applicant: Jaulang Hwang , Chun-Cheng Lin , Hsiao-Ling Chiang , Fan-Dan Jan , Chiao-En Chen , Chia-Tse Shu
Inventor： Jaulang Hwang , Chun-Cheng Lin , Hsiao-Ling Chiang , Fan-Dan Jan , Chiao-En Chen , Chia-Tse Shu
CPC classification number: C07K14/21 , A61K39/00 , A61K39/0011 , C07K14/28 , C07K14/33 , C07K16/3076 , C07K16/3084 , C07K2319/30 , C07K2319/55 , Y02A50/472
Abstract: A protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain. Also described herein is an immunoconjugate containing the protein carrier with an antigen conjugated to multiple cysteine residues in the cysteine-rich domain, and an immune composition containing the immunoconjugate and an adjuvant, as well as their uses in eliciting immune responses.
Abstract translation: 含有抗原呈递细胞结合结构域和富含半胱氨酸的结构域的蛋白质载体。 本文还描述了含有具有与富含半胱氨酸的结构域中的多个半胱氨酸残基缀合的抗原的蛋白质载体的免疫缀合物，以及含有免疫缀合物和佐剂的免疫组合物，以及它们在引发免疫应答中的用途。
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