发明授权
- 专利标题： Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells
- 专利标题（中）： 通过鼻内给药脐带细胞治疗中风和其他急性神经退行性疾病
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申请号： US13184378申请日： 2011-07-15
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公开(公告)号： US08518390B2公开(公告)日： 2013-08-27
- 发明人: Brian C. Kramer , Anthony J. Kihm
- 申请人： Brian C. Kramer , Anthony J. Kihm
- 申请人地址： US MA Raynham
- 专利权人： Advanced Technologies and Regenerative Medicine, LLC
- 当前专利权人： Advanced Technologies and Regenerative Medicine, LLC
- 当前专利权人地址： US MA Raynham
- 代理商 Philip J. Johnson
- 主分类号： C12N5/00
- IPC分类号： C12N5/00 ; C12N5/071
摘要：
This invention relates to methods of treating stroke by intranasal administration of umbilical cord tissue-derived cells, which are isolated from mammalian umbilical cord tissue substantially free of blood or expanded in culture from a cell isolated from mammalian umbilical cord tissue substantially free of blood, are capable of self-renewal and expansion in culture, and do not produce CD117 and/or telomerase. The methods of the invention regenerate, repair and improve neural tissue and improve behavior and neurological function in stroke patients.
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