发明授权
US08541429B2 Pyrazolo quinazoline derivatives, process for their preparation and their use as kinase inhibitors
有权
吡唑喹啉衍生物，其制备方法及其作为激酶抑制剂的用途
- 专利标题： Pyrazolo quinazoline derivatives, process for their preparation and their use as kinase inhibitors
- 专利标题（中）： 吡唑喹啉衍生物，其制备方法及其作为激酶抑制剂的用途
-
申请号： US12262933申请日： 2008-10-31
-
公开(公告)号： US08541429B2公开(公告)日： 2013-09-24
- 发明人: Gabriella Traquandi , Maria Gabriella Brasca , Roberto D'Alessio , Paolo Polucci , Fulvia Roletto , Anna Vulpetti , Paolo Pevarello , Achille Panzeri , Francesca Quartieri , Ron Ferguson , Paola Vianello , Daniele Fancelli
- 申请人： Gabriella Traquandi , Maria Gabriella Brasca , Roberto D'Alessio , Paolo Polucci , Fulvia Roletto , Anna Vulpetti , Paolo Pevarello , Achille Panzeri , Francesca Quartieri , Ron Ferguson , Paola Vianello , Daniele Fancelli
- 申请人地址： IT Nerviano (MI)
- 专利权人： Nerviano Medical Sciences S.R.L.
- 当前专利权人： Nerviano Medical Sciences S.R.L.
- 当前专利权人地址： IT Nerviano (MI)
- 代理机构： Scully, Scott, Murphy & Presser, P.C.
- 主分类号： A01N43/54
- IPC分类号： A01N43/54 ; A61K31/505
摘要：
Pyrazolo-quinazoline derivatives of formula (Ia) or (Ib) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.