发明授权
- 专利标题： Macromolecule transduction domains and methods for identification and uses thereof
- 专利标题（中）： 大分子转导结构域及其鉴定及应用的方法
-
申请号： US12524935申请日： 2008-01-29
-
公开(公告)号： US08629097B2公开(公告)日： 2014-01-14
- 发明人: Dae Woong Jo , Jae Sun Ko , Jin Sook Kim , Kyung Mi Park , Jin Kyung Song , Jung Hee Lim , Thi Thuy Nga Do , Thi Lan Phuong Do , Minh Tam Duong
- 申请人： Dae Woong Jo , Jae Sun Ko , Jin Sook Kim , Kyung Mi Park , Jin Kyung Song , Jung Hee Lim , Thi Thuy Nga Do , Thi Lan Phuong Do , Minh Tam Duong
- 申请人地址： KR Seoul
- 专利权人： Procell Therapeutics Inc.
- 当前专利权人： Procell Therapeutics Inc.
- 当前专利权人地址： KR Seoul
- 代理机构： Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- 国际申请： PCT/KR2008/000525 WO 20080129
- 国际公布： WO2008/093982 WO 20080807
- 主分类号： C07K7/04
- IPC分类号： C07K7/04 ; C07K7/08 ; C07K7/06
摘要：
The present invention discloses novel macromolecule transduction domain (MTD) peptides which facilitate the traverse of a biologically active molecule across the cell membrane. Also disclosed are polynucleotides encoding the MTD peptides, methods of identifying the MTD peptides; methods of genetically engineering a biologically active molecule to have cell permeability by using the MTD peptides, methods of importing a biologically active molecule into a cell by using the MTD peptides, and uses thereof.
公开/授权文献
信息查询
