发明授权
- 专利标题： Hydrazonamide compounds that modulate Hsp90 activity
- 专利标题（中）： 调节Hsp90活性的肼酰胺化合物
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申请号： US13001255申请日： 2009-06-26
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公开(公告)号： US08648071B2公开(公告)日： 2014-02-11
- 发明人: Joseph Burlison , Dinesh U. Chimmanamada , Weiwen Ying , Shijie Zhang , David James
- 申请人： Joseph Burlison , Dinesh U. Chimmanamada , Weiwen Ying , Shijie Zhang , David James
- 申请人地址： US MA Lexington
- 专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人： Synta Pharmaceuticals Corp.
- 当前专利权人地址： US MA Lexington
- 代理机构： McCarter & English, LLP
- 代理商 Steven G. Davis; Mei Bai
- 国际申请： PCT/US2009/003825 WO 20090626
- 国际公布： WO2009/158026 WO 20091230
- 主分类号： A61K31/5375
- IPC分类号： A61K31/5375 ; A61K31/5377 ; A61K31/445 ; A61K31/357 ; C07D413/00 ; C07D413/02 ; C07D295/00 ; C07D211/00 ; C07D317/46
摘要：
The present invention relates to substituted hydrazonamide compounds. The invention further relates to methods of inhibiting the activity of Hsρ90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted hydrazonamide compound of the invention, or a pharmaceutical composition comprising such a compound.
公开/授权文献
- US20120046288A1 Hydrazonamide Compounds That Modulate Hsp90 Activity 公开/授权日：2012-02-23
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