发明授权
- 专利标题: Selection system
- 专利标题(中): 选拔制度
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申请号: US12246741申请日: 2008-10-07
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公开(公告)号: US08680018B2公开(公告)日: 2014-03-25
- 发明人: Lutz Reichmann , Peter Kristensen , Jean-Luc Jestin , Gregory Paul Winter
- 申请人: Lutz Reichmann , Peter Kristensen , Jean-Luc Jestin , Gregory Paul Winter
- 申请人地址: GB Brentford, Middlesex
- 专利权人: Domantis Limited
- 当前专利权人: Domantis Limited
- 当前专利权人地址: GB Brentford, Middlesex
- 代理商 Jason C. Fedon; William T. Han
- 优先权: GB9810223.9 19980513; GB9810228.8 19980513
- 主分类号: C40B30/06
- IPC分类号: C40B30/06
摘要:
The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.
公开/授权文献
- US20090203542A1 SELECTION SYSTEM 公开/授权日:2009-08-13
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