Polypeptide
    5.
    发明申请
    Polypeptide 审中-公开
    多肽

    公开(公告)号:US20080103055A1

    公开(公告)日:2008-05-01

    申请号:US11654205

    申请日:2007-01-16

    申请人: Peter Kristensen

    发明人: Peter Kristensen

    CPC分类号: C12N15/1044 C07K2318/20

    摘要: The present invention relates to a novel polypeptide chain forming a particular 3 dimensional fold characterized by a β-sandwich. By altering the amino acid sequence in specific regions of the polypeptide of the invention novel binding characteristics are developed. Methods for the generation of a polypeptide according to the invention and uses of polypeptides of the invention are also described.

    摘要翻译: 本发明涉及一种形成以β-三明治为特征的特定3维折叠的新型多肽链。 通过改变本发明多肽的特定区域中的氨基酸序列,开发了新的结合特征。 还描述了产生本发明多肽的方法和本发明多肽的用途。

    DETECTION OF FETAL CELLS FROM MATERNAL BLOOD
    7.
    发明申请
    DETECTION OF FETAL CELLS FROM MATERNAL BLOOD 有权
    从母体血液中检测胎儿细胞

    公开(公告)号:US20120070827A1

    公开(公告)日:2012-03-22

    申请号:US13169922

    申请日:2011-06-27

    摘要: The present application relates to methods for identification of foetal cells and generation and isolation of binding members recognising foetal cells. Said methods may further be used for other purposes relating to characterisation of biological samples and biological antigens. The methods are characterised by the applicability in situations where the interesting objects are present in a limited amount, or where the interesting objects are intermixed with other material, thus the methods are suitable for use in situations where the ratio of the interesting material compared to other material is low. The application discloses methods for use of detecting foetal cells and method of generating/isolating binding members towards antigenic material of low abundancy.

    摘要翻译: 本申请涉及用于鉴定胎儿细胞的方法以及识别胎儿细胞的结合成员的产生和分离。 所述方法还可用于与生物样品和生物抗原的表征有关的其它目的。 这些方法的特征在于在感兴趣的对象以有限的量存在的情况下或者有趣的对象与其他材料混合的情况下的适用性,因此该方法适用于将感兴趣的材料与其他材料相比较的情况 材料低 本申请公开了用于检测胎儿细胞的方法以及将结合成员产生/分离成低丰度抗原物质的方法。